Occupational stress is on the rise in Western societies, as such, this double-blind, randomised, placebo-controlled study aimed to determine if a high dose vitamin B complex had a positive effect on mood and psychological strain associated with chronic work stress.

Sixty participants were randomly allocated to either a treatment or placebo group.

Results demonstrated that those in the treatment groups had significantly lower personal strain and a reduction in low mood after 12 weeks.


Stough, C., Scholey, A., Lloyd, J., Spong, J., Myers, S., & Downey, L. A. (2011). The effect of 90 day administration of a high dose vitamin B-complex on work stress. Human Psychopharmacology, 26, 470-476. Doi: 10.1002/hup.1229